Evaluation of wound healing activity of the plant Carmona retusa (Vahl) Masam., in mice

The evaluation of wound healing activity was conducted to study the effect of various extracts of Carmona retusa (Vahl) Masam. The ointment was prepared from the alcohol extract of root, stem and leaves with petroleum jelly as a base in 5% and 10% concentrations. Swiss albino mice were used for the evaluation of wound healing activity. The ointment prepared from various parts exhibited considerable response when compared with standard drug Nitrofurazone (0.2%) ointment in terms of wound contracting ability and wound closure time. Remarkable wound healing activity was observed with the root extract ointment at 5% and 10% concentration. This result showed that the ointment of plant extracts accelerate the wound healing process and specifically increased the epithelization in treatment groups when compared with control groups. Thus, this wound healing evaluation study demonstrates that C. retusa is effective in stimulating the closure of wounds. © 2012 Editor-IJIIT. Hosting by AGSI Publications. All rights reserved. How to cite this article: S Mageswari, S Karpagam and G Aadinaath Reddy (2015). Evaluation of wound healing activity of the plant Carmona retusa (Vahl) Masam., in mice, International Journal of integrative Sciences, Innovation and Technology (IJIIT), 4(5), 1 4.